Growth factors are small proteins capable of stimulating cellular growth. They are in greater proportion contained in platelets. When these substances bind with the receptors of a cell membrane, the cell is activated and it stimulates collagen production. Topical injection of growth factors seem to produce significant benefits on aging skin: it restores skin vitality, increases thickness and recovers elasticity. Growth factors are obtained from the patient’s own blood. The advantage of using these growth factors in anti-aging treatment is to provide a completely personal biological substance manufactured in one’s own body, it is free from chemicals and almost risk-free. Treatment of platelet-rich plasma produces excellent results, which are visible from the 30th day of administration.